Comparison of Two Specific Allergen Screening Tests in Different Patient Groups

兩種特異性過敏原篩選試驗在不同病患群組之比較

劉伊薰(Yi-Hsun Liu) ； 周信旭(Hsin-Hsu Chou) ； 詹仁隆(Ren-Long Jan) ； 林慧娟(Huey-Juan Lin) ； 梁純淨(Chun-Ching Liang) ； 王志堯(Ji-Yao Wang) ； 吳郁青(Yu-Ching Wu) ； 謝奇璋(Chi-Chang Shieh)

《Acta Paediatrica Taiwanica》 47卷3期 (2006/06) Pp. 116-122

https://doi.org/10.7097/APT.200606.0116

並列摘要

UniCAP and multiple-antigen simultaneous test (MAST) are among the widely used specific allergen tests. The Phadiatop and Fx5 are the multi-allergen UniCAP screening tests for inhalant allergens and common food allergens, respectively. We compared the differences between Phadiatop-Fx5 and MAST as screening allergen tests to clarify the optimal tests for different groups of allergic patients. Serum samples of 224 consecutive allergic patients were tested with Phadiatop, Fx5 and MAST. Results of these allergen tests were compared and analyzed in subgroups categorized by age, serum IgE levels and the clinical departments where the patients were treated. We found that among the 224 patients, 155 patients (69.2%) tested positive with Phadiatop while 137 (61.1%) tested positive with MAST for inhalant allergens. Twenty patients were Phadiatop(+)/MAST(-), while only 2 were Phadiatop(-)/MAST(+). There were 57 patients (25.4%) who tested positive with Fx5, while 32 (14.3%) tested positive with MAST for food allergens. Thirty-eight patients were Fx5(+)/MAST(-), while 13 were Fx5(-)/MAST(+). The disagreement between these two tests was more apparent in food allergen tests than in inhalant allergen tests. Most cases of disagreement occurred in younger age groups and in the patient group with IgE ＞ 500 IU/ml. These results suggested that UniCAP allergen screening tests might be more effective in certain patient groups as screening tests.

並列關鍵字

phadiatop ； UniCAP ； MAST ； specific allergen test