透過您的圖書館登入
IP:18.191.228.88
  • 期刊

EDTA-dependent Pseudothrombocytopenia in a Patient with Systemic Lupus Erythematosus

抗凝劑相關之偽性血小板減少症發現於系統性紅斑性狼瘡病人:個例報告

摘要


抗凝劑可能會導致體外的偽性血小板減少症,而血小板減少症是系統性紅斑性狼瘡病人經常伴隨的血液症狀之一,所以臨床上鑑別抗凝劑導致偽性血小板減少症或真實的血小板減少症極為重要,可減少病人不必要的檢查或治療。本文將報告一位表現偽性血小板減少症之系統性紅斑性狼瘡病人,其血小板在抗凝劑中凝集的狀況受時間及溫度之影響。

並列摘要


Here we present pseudothrombocytopenia (PTCP) of blood samples in the presence of ethylenediaminetetraacetic acid (EDTA) in a patient with systemic lupus erythematosus. Fluctuating low platelet counts not correlated with the clinical presentation were found in routine complete blood counting on an automated cell counter. Platelet clumps were identified on peripheral blood smears. PTCP in this patient was recognized to occur rapidly in the blood samples anticoagulated with EDTA and was found to be time and temperature-dependent. Moreover, the phenomenon of PTCP was not reversible, irrespective of temperature, once the platelet clumping had taken place. Although PTCP is devoid of pathological significance, identification of PTCP is important and of clinical significance to avoid unnecessary investigations and medical management on spurious thrombocytopenia.

延伸閱讀