The aim of the study was to compare glucose tolerance and insulin response between mid-age and young adult subjects with different levels of physical activity. Forty-five subjects including sedentary college students (Young-sedentary, age 20±0.1), college swimmers (Young-active, age 21±0.5), sedentary college professors (Mid-age-sedentary, age 42±3.1, N=10), and college coaches (Mid-age-active, 41±2.8, N=8) participated this study. Oral glucose tolerance test (OGTT) and insulin response was used to determine insulin sensitivity of these subjects. Blood cholesterol and triglycerides were also measured under fasted condition. In both age levels, physically active subjects displayed significantly lower insulin response during OGTT than sedentary subjects. Negative correlation between weekly exercise time and insulin level during OGTT was observed in both age group, but the correlation value was greater in mid-age groups (R=0.73, P<0.01) than in young groups (R=0.37, no significance). Similarly, blood triglyceride level was significantly correlated to WHR, and this correlation value was also greater in mid-age groups than in young groups. Additionally, blood triglyceride level in young subjects appears to be more associated with body composition instead of weekly exercise time.
The aim of the study was to compare glucose tolerance and insulin response between mid-age and young adult subjects with different levels of physical activity. Forty-five subjects including sedentary college students (Young-sedentary, age 20±0.1), college swimmers (Young-active, age 21±0.5), sedentary college professors (Mid-age-sedentary, age 42±3.1, N=10), and college coaches (Mid-age-active, 41±2.8, N=8) participated this study. Oral glucose tolerance test (OGTT) and insulin response was used to determine insulin sensitivity of these subjects. Blood cholesterol and triglycerides were also measured under fasted condition. In both age levels, physically active subjects displayed significantly lower insulin response during OGTT than sedentary subjects. Negative correlation between weekly exercise time and insulin level during OGTT was observed in both age group, but the correlation value was greater in mid-age groups (R=0.73, P<0.01) than in young groups (R=0.37, no significance). Similarly, blood triglyceride level was significantly correlated to WHR, and this correlation value was also greater in mid-age groups than in young groups. Additionally, blood triglyceride level in young subjects appears to be more associated with body composition instead of weekly exercise time.