運動訓練對於壽命指標之影響

The Effect of Exercise Training on Longevity Markers

李若屏(Jo-Ping Lee) ； 黃奕仁(Yi-Jen Huang) ； 陳慕聰(Mu-Tsung Chen) ； 李毓國(Yu-Kuo Lee) ； 方進隆(Chin-Lung Fang)

《北體學報》 16期 (2008/12) Pp. 126-138

https://doi.org/10.6167/TPEC/2008.16.12

摘要

Longevity was correlated with metabolic fitness which could be improved via exercise. Fasting insulin and DHEA-S had been regarded as longevity markers. This study tempted to investigate the effect of exercise training on human longevity. Twenty-four elderly (aged 71.5±0.9, BMI=25.5±0.7kg/m^2) were recruited to involve in 16-week low-to-moderate intensity exercise training. Fasting insulin, DHEA-S and markers related to metabolic fitness including glucose tolerance, insulin sensitivity, blood pressure, blood lipid and cortisol were measured pre- and post- exercise training. DHEA-S increased from 3.98±1.27ng/ml to 9.14±1.86ng/ml (p=0.027) but fasting insulin had no significant change from 8.9±1.0 μU/ml to 8.8±0.6 μU/ml (p=0.779). No significant difference was also noted in metabolic fitness but fasting glucose, diastolic blood pressure, cholesterol significantly decreased (p＜0.05). Cortisol had no significant decrease from 0.89±0.25mg/ml to 0.53±0.05ng/ml (p=0.175). The present results suggested that moderate-low exercise training could prevent age-related metabolic dysfunction via enhance DHEA-S and lowering the risk factors relevant to chronic diseases.

關鍵字

運動訓練 ； 壽命指標 ； 代謝適能

並列摘要

Longevity was correlated with metabolic fitness which could be improved via exercise. Fasting insulin and DHEA-S had been regarded as longevity markers. This study tempted to investigate the effect of exercise training on human longevity. Twenty-four elderly (aged 71.5±0.9, BMI=25.5±0.7kg/m^2) were recruited to involve in 16-week low-to-moderate intensity exercise training. Fasting insulin, DHEA-S and markers related to metabolic fitness including glucose tolerance, insulin sensitivity, blood pressure, blood lipid and cortisol were measured pre- and post- exercise training. DHEA-S increased from 3.98±1.27ng/ml to 9.14±1.86ng/ml (p=0.027) but fasting insulin had no significant change from 8.9±1.0 μU/ml to 8.8±0.6 μU/ml (p=0.779). No significant difference was also noted in metabolic fitness but fasting glucose, diastolic blood pressure, cholesterol significantly decreased (p＜0.05). Cortisol had no significant decrease from 0.89±0.25mg/ml to 0.53±0.05ng/ml (p=0.175). The present results suggested that moderate-low exercise training could prevent age-related metabolic dysfunction via enhance DHEA-S and lowering the risk factors relevant to chronic diseases.

並列關鍵字

exercise training ； longevity marker ； metabolic fitness

參考文獻

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