Early detection and early diagnosis of dementia are critical. A dementia screening program co-organized by Kiang Wu Nursing College of Macau, Dr. Stanley Ho Medical Development Foundation and Macau Alzheimer's Disease Association was conducted in three community centers at Macao from November 2016 to June 2017, aiming to identify early cases of dementia in the community and promote early detection and diagnosis of dementia. A total of 257 participants were screened, and 90 of them were dementia suspicious cases in terms of cognitive function. This article described the background, process and results of the screening program. And it suggested that the early detection and diagnosis of dementia can be achieved by strengthening community empowerment, public education and support after screening, and creating a dementia-friendly social atmosphere. In addition, screening tools should be carefully selected based on the scale of screening, community population characteristics, and other factors.