This article described a nursing experience of caring a hospitalized elder with organic delirium. To establish the sense of comfort and trust, therapeutic relationship was applied to the client. During one-month period, four nursing diagnoses were made, including sleep-pattern disturbance, self-care deficit, thought process disturbance and disabling family coping. The nurse planned individual interventions, taught the client's family how to manage her syndromes, and solved the client's problems. Therefore, a therapeutic relationship and individual nursing interventions are the most important things in caring a delirium client. The author would like to present this case report to other professional nurses.