乳癌婦女接受化學治療導致手足症候群臨床評估及護理處置

Clinical Evaluation and Nursing Management of Hand Foot Syndrome in Breast Cancer Patients Received Chemotherapy

許雅惠(Ya-Hui Hsu) ； 沈雯琪(Wen-Chi Shen) ； 陳淑卿(Shu-Ching Chen)

《腫瘤護理雜誌》 17卷2期 (2017/12) Pp. 17-26

https://doi.org/10.3966/168395442017121702002

摘要

手足症候群是使用聚乙二醇化的脂質體阿黴素（pegylated liposomal doxorubicin, PLD）、截瘤達（capecitabine）和5-FU、德薩（Cytarabine）及紫杉醇（docetaxel）等化學治療藥物引起的皮膚毒性反應，會影響執行日常活動及導致生活品質降低，可能導致治療中斷或影響治療療效。本文主要探討化學治療導致手足症候群病理生理機轉、臨床表徵、主客觀評估工具及處置，期能提供護理人員臨床照護參考。

關鍵字

乳癌 ； 化學治療 ； 手足症候群 ； 皮膚毒性反應

並列摘要

Hand-foot syndrome (HFD) is a skin toxicity reaction caused by chemotherapy such as pegylated liposomal doxorubicin (PLD), capecitabine, 5-FU, cytarabine, and docetaxel. Hand-foot syndrome often interferes with daily life and has negative impacts on the quality of life. These conditions, as a result, may lead to interruption of treatment and negative treatment efficacy. This article aimed to explore the pathology mechanism, symptom, subjective and objective assessment tools and related management. This article should help nurses as a reference in caring for similar patients in the future.

並列關鍵字

chemotherapy ； skin toxicity reaction ； clinical evaluation ； nursing management

參考文獻

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