On basis of the comparison of symptoms and signs, this article describes the treatment strategies used in ”Shang Horn Tzar Bing Luenn” for ”Wun Bing (the epidemic diseases accompanied by fever)” and the erroneous zone of the traditional treatments for these diseases. The conclusion regarding to this research points out that physicians practicing modem traditional Chinese medicine (TCM) no matter in the fields of clinic, research, or teaching should focus on the symptoms and signs of diseases and deepen the understanding of relationship between the symptoms, signs, and Fang Ji and implement the unique TCM theory of ”Has such symptoms and signs to use such medicine”. By doing so, it is expected to enhance the curative effect in clinic and shorten the learning period of the beginners.