評估雙能量X光骨質密度儀及定量超音波骨質密度儀對服用龜鹿二仙膠後停經婦女骨質密度的影響

The Effect of Guilu Erxian Decoction on Bone Mineral Density in Postmenopausal Women Evaluated Using Dual Energy X-ray Absorptiometry and Quantitative Ultrasound

黎榮興(Rung-Shing Li) ； 許忠源(Jung-Yuan Shyu) ； 孫盛義(Seng-Yih Sun) ； 何豐名(Feng-Ming Ho) ； 王士豪(Shyh-Hau Wang)

《中華放射線技術學雜誌》 31卷2期 (2007/12) Pp. 147-153

https://doi.org/10.30045/CJRT.200712.0009

摘要

In 64 postmenopausal women (aged 54.8±6.6), double blind randomly assigned to treat with Guilu Erxian Decoction or placebo, individually, administered 3.1 g thrice daily for 12 weeks. The bone mineral density measurements (BMD) of the Dual Energy X-ray Absorptiometry (DXA) lumbar spine (L1-L4) and femoral neck were obtained, and quantitative ultrasound (QUS) was performed to determine the BUA and T-score of the calcaneus at 0 and 12 weeks. RESULTS: Thirty-two participants showed progressive increase of BMD after treatment with Guilu Erxian Decoction. After 12 weeks treatment, mean BMD had increased significantly (p＜0.01) at the lumbar spine (1.15%), femoral neck (1.11%), and mean BUA had increased significantly (p＜0.01) at calcaneus (3.26%) in the treated group. Increases in BMD were significantly (p＜0.01) greater than in the placebo group at all sites.

關鍵字

骨質疏鬆症 ； 停經後婦女 ； 龜鹿二仙膠 ； 雙能量X光骨質密度儀 ； 定量超音波

並列摘要

In 64 postmenopausal women (aged 54.8±6.6), double blind randomly assigned to treat with Guilu Erxian Decoction or placebo, individually, administered 3.1 g thrice daily for 12 weeks. The bone mineral density measurements (BMD) of the Dual Energy X-ray Absorptiometry (DXA) lumbar spine (L1-L4) and femoral neck were obtained, and quantitative ultrasound (QUS) was performed to determine the BUA and T-score of the calcaneus at 0 and 12 weeks. RESULTS: Thirty-two participants showed progressive increase of BMD after treatment with Guilu Erxian Decoction. After 12 weeks treatment, mean BMD had increased significantly (p＜0.01) at the lumbar spine (1.15%), femoral neck (1.11%), and mean BUA had increased significantly (p＜0.01) at calcaneus (3.26%) in the treated group. Increases in BMD were significantly (p＜0.01) greater than in the placebo group at all sites.

並列關鍵字

osteoporosis ； postmenopausal women ； guilu erxian decoction ； DXA ； QUS