This aim of this study was to improve diagnostic accuracy in benign and malignant of thyroid nodules by using the technique of ultrasound (US) elastography and conventional ultrasound. Fifty-nine consecutive patients (17 males and 42 female, aged 14-83 years) were enrolled in the study. B-mode US was performed for initial detection of thyroid nodules. Color Doppler US (CDUS) was applied to evaluate blood flow within the detected lesions. US-elastography was applied to evaluate the hardness of the nodules. The hardness of the nodules was further defined by using elastographic score (ES), in the color scale that was classified into 5 grades, red-colored for component with hard consistency, and green-colored for soft consistency. Pearson chi-square test was performed by statistically significant result (ρ<0.05). Based on diagnosis results, 64 nodules from 59 patients were divided into four groups: cystic nodules, inflammatory nodules, benign nodules and malignant nodules. Presence of halo sign, echo pattern, blood flow in CDUS, and two patterns of US-elastography were statistically significant (ρ<0.05). US-Elastography of cystic nodules showed three features: mixed signal sign, duplicated nodal sign, and white-band signal sign of images displacement. The ES grades of thyroid inflammatory nodules were related to different degree of tissue. ES grade of 4-5 were highly predictive of malignant nodules. Our results demonstrated that US-elastography was a useful tool on the assessment of benign and malignant thyroid nodules. Combined of different ultrasound modalities, including B-mode, CDUS and US-elastography, have the potential to substantially reduce the number of fine needle aspiration for thyroid nodules..
This aim of this study was to improve diagnostic accuracy in benign and malignant of thyroid nodules by using the technique of ultrasound (US) elastography and conventional ultrasound. Fifty-nine consecutive patients (17 males and 42 female, aged 14-83 years) were enrolled in the study. B-mode US was performed for initial detection of thyroid nodules. Color Doppler US (CDUS) was applied to evaluate blood flow within the detected lesions. US-elastography was applied to evaluate the hardness of the nodules. The hardness of the nodules was further defined by using elastographic score (ES), in the color scale that was classified into 5 grades, red-colored for component with hard consistency, and green-colored for soft consistency. Pearson chi-square test was performed by statistically significant result (ρ<0.05). Based on diagnosis results, 64 nodules from 59 patients were divided into four groups: cystic nodules, inflammatory nodules, benign nodules and malignant nodules. Presence of halo sign, echo pattern, blood flow in CDUS, and two patterns of US-elastography were statistically significant (ρ<0.05). US-Elastography of cystic nodules showed three features: mixed signal sign, duplicated nodal sign, and white-band signal sign of images displacement. The ES grades of thyroid inflammatory nodules were related to different degree of tissue. ES grade of 4-5 were highly predictive of malignant nodules. Our results demonstrated that US-elastography was a useful tool on the assessment of benign and malignant thyroid nodules. Combined of different ultrasound modalities, including B-mode, CDUS and US-elastography, have the potential to substantially reduce the number of fine needle aspiration for thyroid nodules..