以像素值評估婦女乳房組織中乳腺及脂肪比例

Evaluation of the Proportion of Mammary Gland and Fatty Tissue with Pixel Assessment

趙真(Chen Chao) ； 田雨生(Yeu-Sheng Tyan) ； 蘇冠豪(Kuan-Hao Su) ； 張振莒(Chen-Chu Chang) ； 鄭凱元(Kai-Yuan Cheng)

《中華放射線技術學雜誌》 36卷1期 (2012/03) Pp. 21-26

https://doi.org/10.30045/CJRT.201203.0004

摘要

依近年國內外文獻顯示，乳房X光攝影是乳癌最主要的篩檢工具。目前國內進行乳房攝影影像之品質評估作業，皆利用50%脂肪－50%乳腺的假體來測試及校正。本研究目的在於分析國內婦女乳腺－脂肪比例，經由研究結果進而選擇適合之假體來進行儀器品管測試，藉以確保在不同的乳房乳腺密度比例下，儀器仍能維持最佳之影像品質及劑量輸出之穩定性。本研究利用模擬人類乳房組成，內含不同平均腺體組織的乳房組織當量假體（tissue-equivalent phantom），以數位乳房X光機進行攝影，分析假體中不同乳腺比例區域之像素平均值。以回溯的方式，將335位婦女未經處理的乳房Ｘ光影像（raw image），利用Matlab程式推估乳腺、脂肪比例。結果顯示，33位不同年齡層受檢者之乳腺推估比例為：40-49歲29.84%、50-59歲15.47%、60-69 歲10.66%。3位醫事放射師對臨床影像之判定等級，與經由像素值推估之乳腺、脂肪比例等級，結果顯示經Kendall和諧係數檢定（P＜0.005），具顯著相關。顯示國內婦女乳腺與脂肪之比例並非50％-50%組成，如能選擇適合之假體進行儀器品管測試，並調整最佳之攝影參數降低乳腺劑量，將可讓乳房攝影品管作業更臻完善。

關鍵字

乳房攝影 ； 乳腺密度 ； 像素值

並列摘要

Recent studies have indicated that mammography is still the major screening tool for breast cancer. The aim of this study is to analyze the glandular/adipose composition ratio in the breast of women in Taiwan to further select the suitable phantom for the quality assurance of mammography, and also ensure the best image quality and stable of the mammography equipment when analyzing various breast densities. In this study, we selected the Tissue-Equivalent Phantom with different glandular/adipose composition that mimics the human breast tissue and examined it through the digital mammography that took the image and analyzed it through pixel values in area with different degrees of glandular and adipose ratio compositions were evaluated through the Matlab system. The results showed the glandular compositions of the 335 tests women of different ages were: 29.84 % for 40-49 years old; 15.47 % for 50-59 years old; 10.66 % for 60-69 years old. The results also showed that the level of estimated glandular and adipose ratio determined by the three radiological technologists was similar, the Kendall’s coefficient of concordance test (p ＜0.005), with significant correlation. According to this study, the ratio of glandular and adipose in Taiwanese women was not composed of 50% to 50% ratio. If an appropriate phantom can be selected for mammography to lower the glandular dosage, the process and results of mammography can also be improved.

並列關鍵字

mammography ； breast density ； pixel value