以磁振造影技術分析椎間盤退化與腰椎多裂肌萎縮對下背痛的影響並評估其相關性

Using MRI to Analyze the Influence of Intervertebral Disc Degeneration and Multifidus Muscle Atrophy on Lower Back Pain and their Relationship

王基誠(Chi-Cheng Wang) ； 廖阡佑(Chien-Yu Liao) ； 黃武達(Wou-Da Hwang) ； 陳素秋(Su-Chiou Chen) ； 楊斐適(Fei-Shih Yang) ； 莊奇容(Chi-Long Juang)

《中華放射線技術學雜誌》 37卷2期 (2013/06) Pp. 83-89

摘要

This study investigates the correlation between disk degeneration and fatty infiltration of the lumbar multifidus muscles. Results will helpfully serve as a reference for clinical physicians during disk degeneration diagnosis and treatment method selection. Philips 3.0T magnetic resonance imaging (MRI) was employed as the measuring equipment. Techniques, including non-invasive T2 relaxation time map (T2 Map), T1W and T2W images, were utilized to quantify and analyze the degeneration level of the intervertebral disks. Additionally, proton magnetic resonance spectroscopy (1H MRS) was performed to analyze variations in the lumbar multifidus muscles. Subjects aged 20 to 50 were divided into two groups, each with 30 participants: an experimental group that expressed complaints regarding lower back pain, and a control group that did not experience lower back pain. The study results showed that individuals with lower back pain had significantly lower T2 (80.3 versus 99.2 ms, p ＜ 0.01) for the nucleus pulposus compared to that of healthy people. However, the fat content of multifidus muscles did not differ significantly between groups (18.0% versus 13.5%, p = 0.085). We found that disability index for lower back pain was negatively and significantly correlated with T2 for the nucleus pulposus, with a correlation coefficient of -0.426 (p ＜ 0.01). Conversely, it was positively and significantly correlated with BMI, age, and the fat content of multifidus muscles, with the correlation coefficients 0.272 (p ＜ 0.05), 0.400 (p ＜ 0.01), and 0.393 (p ＜ 0.01), respectively. Furthermore, the T2 values for the nucleus pulposus of L1 to S1 of the intervertebral disc in people with lower back pain was also significantly lower than that in healthy people, indicating that the water content of the nucleus pulposus for patients with lower back pain was less than that for healthy individuals. When T2 for the nucleus pulposus decreases, or when the fat content of multifidus muscles increases, the influence that lower back pain has on daily life is exacerbated.

關鍵字

椎間盤退化 ； 磁振造影 ； T2弛豫時間圖像 ； 腰椎多裂肌 ； 氫磁振頻譜

並列摘要

This study investigates the correlation between disk degeneration and fatty infiltration of the lumbar multifidus muscles. Results will helpfully serve as a reference for clinical physicians during disk degeneration diagnosis and treatment method selection. Philips 3.0T magnetic resonance imaging (MRI) was employed as the measuring equipment. Techniques, including non-invasive T2 relaxation time map (T2 Map), T1W and T2W images, were utilized to quantify and analyze the degeneration level of the intervertebral disks. Additionally, proton magnetic resonance spectroscopy (1H MRS) was performed to analyze variations in the lumbar multifidus muscles. Subjects aged 20 to 50 were divided into two groups, each with 30 participants: an experimental group that expressed complaints regarding lower back pain, and a control group that did not experience lower back pain. The study results showed that individuals with lower back pain had significantly lower T2 (80.3 versus 99.2 ms, p ＜ 0.01) for the nucleus pulposus compared to that of healthy people. However, the fat content of multifidus muscles did not differ significantly between groups (18.0% versus 13.5%, p = 0.085). We found that disability index for lower back pain was negatively and significantly correlated with T2 for the nucleus pulposus, with a correlation coefficient of -0.426 (p ＜ 0.01). Conversely, it was positively and significantly correlated with BMI, age, and the fat content of multifidus muscles, with the correlation coefficients 0.272 (p ＜ 0.05), 0.400 (p ＜ 0.01), and 0.393 (p ＜ 0.01), respectively. Furthermore, the T2 values for the nucleus pulposus of L1 to S1 of the intervertebral disc in people with lower back pain was also significantly lower than that in healthy people, indicating that the water content of the nucleus pulposus for patients with lower back pain was less than that for healthy individuals. When T2 for the nucleus pulposus decreases, or when the fat content of multifidus muscles increases, the influence that lower back pain has on daily life is exacerbated.

並列關鍵字

intervertebral disc degeneration ； magnetic resonance imaging ； T2 relaxation time calculated map ； multifidus muscles ； proton magnetic resonance spectroscopy