溫泉水抗氧化及抗致突變之研究以耕莘專校宜蘭校區溫泉水為例

溫泉浴與溫泉水療(SPA)的休閒近年來席捲全台，溫泉成為觀光業者最熱門的產業。過去學者研究證實碳酸氫鹽泉具有吸收氫氧自由基之抗氧化作用，而紫外線及自由基是導致皮膚黑色素生成的重要因素，抗氧化與抗致突變活性為正相關性，故本研究以耕莘健康管理專科學校宜蘭校區溫泉水(hot-spring water; HSW)為例，針對溫泉水之抗氧化與抗致突變性進行活性效能的評估。結果證實，10.0 mg/mL溫泉水萃取物清除DPPH自由基的效果相當於同濃度Ascorbicacid的60.40%；此外溫泉水不具致突變性，且2.5 mg/plate溫泉水萃取物對sodium azide引起致沙門氏菌TA100突變的抑制率為55.5%，屬於中度活性的抑制作用(抑制率≧40%)。綜合上述結果，溫泉水萃取物應可考量作為一安全而具有化學防護效果的天然保健素材。

關鍵字

溫泉水；抗氧化；抗致突變性

並列摘要

In recent years, spa bath and spa (SPA) have swept across Taiwan's leisure and spa tourism industry, which have become the most popular and profitable products. Some scholars´ studies confirmed that bicarbonate salt spring has the hydroxyl radical scavenging activity. The UV rays and free radicals are important factors leading to skin melanin. There is a positive correlation between antioxidant and antimutagenic activity. In this study, we investigate the capacity of antioxidant and antimutagenicity in hot-spring water (HSW) in Yilan campus at Cardinal Tien Junior College of Healthcare and Management. These results suggest that in the concentration of 10.0 mg/mL, the ability of the hot-spring water extract for the scavenging DPPH free radicals is 60.40% to Ascorbic acid. In addition, the hot-spring water does not possess mutagenicity. The suppressing rate of the hot-spring water extract with 2.5 mg/plate for the mutation of Salmonella typhimurium TA100 caused by sodium azide is 55.5% which is higher than 40%, suggesting that the hot-spring water belongs to the positive activity group of antimutagenicity. In conclusion, the hot-spring water extract may be a safe, natural, and healthy material for keeping genes in cells from chemical injury.

並列關鍵字

Hot-spring water ； Antioxidation ； Antimutagenicity

國際替代計量

溫泉水抗氧化及抗致突變之研究以耕莘專校宜蘭校區溫泉水為例

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