Development of a Rapid Screening Tool for Mild Cognitive Impairment: Validation of a Computer-Based Short-Term Memory Test

輕度認知障礙症的快篩：電腦版短期記憶測驗之效度研究

葉炳強(Ping-Keung Yip) ； 陳志豪(Chih-Hao Chen) ； 王國慶(Kaw-Chen Wang) ； 羅巧妤(Chiao-Yu Lo) ； 葉在庭(Zai-Ting Yeh)

《輔仁醫學期刊》 15卷1期 (2017/03) Pp. 1-10

https://doi.org/10.3966/181020932017031501001

摘要

Background and purpose: With advancements in technology, computer use is becoming ubiquitous. The present study developed a computer-based short-term memory (CBSTM) test for screening for mild cognitive impairment (MCI). The study was designed to assess the psychometric properties of the CB-STM test, including temporal reliability and concurrent validity. Methods: The study sample comprised 69 elderly participants (age: 60- 94 years), including 17 patients with mild possible dementia, 22 patients with MCI, and 30 normal controls (NCs). Results: The CB-STM test demonstrated adequate test-retest reliability (.75) and high internal consistency (.83-.85), as well as adequate sensitivity and specificity for differentiating between the NC, MCI, and mild possible dementia groups. Conclusions: Twenty points in the CB-STM test is suggested to generate sufficient balance sensitivity (76%) and specificity (73%) for differentiating between NCs and patients with MCI, and 13 points is suggested to generate sufficient sensitivity (77%) and specificity (77%) for distinguishing between patients with MCI and those with Alzheimer disease.

關鍵字

Neuropsychological assessment ； computer-based short-term memory test ； mild cognitive impairment ； screening mild possible dementia

並列摘要

背景和目的：隨著技術的進步，電腦的使用變得無處不在，本研究目的是發展篩選輕度認知損傷之電腦版短期記憶測驗 (CB-STM)，並且進行信度及效度的檢驗。方法：研究樣本包括64位年齡介於60至94歲的老年人，其中有17位輕度阿茲海默型失智症，22位輕度認知障礙症患者和25位健康對照組。結果：CB-STM具有良好的再測信度（.75）和高度的內部一致性系數（.83-.85）。該測驗對於區分正常老年人，輕度認知功能障礙和輕度失智症患間也具有良好的敏感度和特異度。結論：切截分數為20分時，能有效區分正常老年人與輕度認知功能障礙，其敏感度為76%，特異度為73%；切截分數為13分時，其敏感度為77%，特異度為77%。

並列關鍵字

臨床神經心理學評估 ； 電腦版短期記憶測驗 ； 輕度認知障礙 ； 失智症快篩