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Thyroglossal Duct Cyst Carcinoma: Case Report and Treatment Discussion

甲狀舌骨囊腫惡性腫瘤:個案報告及治療討論

摘要


Thyroglossal duct cyst (TGDC) is the most common congenital thyroid developmental anomaly and also the most common congenital neck anomaly. Incidence of TGDC in the adult population is estimated at 7%. However, malignant changes are rare and occur in less than 1% of TGDC. Over 90% comprises papillary types while squamous cell carcinoma comprises 4.3%. Here we report the case of a 52-year-old female with unexpected finding of papillary carcinoma arising from TGDC. Subsequent total thyroidectomy and radioactive iodine treatment is performed.

並列摘要


甲狀舌骨囊腫是最常見的甲狀腺先天性異常,發生率在成人約佔7%左右。其大多為前頸部無症狀之良性腫塊,而惡性變化則相當少見,一般來說發生率低於1%。組織類型上超過九成皆為乳突細胞型,約有4%為鱗狀細胞癌。對於此惡性腫瘤的治療上,除了完整的手術切除外,是否需合併甲狀腺組織的切除,及術後輔助性放射碘治療,至今仍存在許多爭議。在此,我們報告一個52歲女性之甲狀舌骨囊腫的甲狀腺乳突癌病患,並對其臨床診斷及治療方式提出討論。

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