Pilomatricoma of the Eyelid and Eyebrow in an Adult Male

眼瞼毛髮編織瘤源自於毛囊的良性皮膚腫瘤，臨床上好發於女童，罕見於成人男性。本文病例報告一位32歲男性右眼患有眼瞼毛髮編織瘤，探討該患者臨床特徵、組織病理特徵以及治療成效。並文獻回顧，依年齡分成三組：兒童組（小於21歲）、成人組（介於21至50歲）及老年人組（大於50歲），比較此三組的臨床特徵、術前診斷、鑑別診斷、組織病理特徵以及治療成效的異同之處。我們發現：雖然臨床上眼瞼毛髮編織瘤罕見於成人男性，但是臨床特徵、術前診斷、鑑別診斷、組織病理特徵以及治療成效，皆類似於其他兩組。除了，少部分非典型臨床特徵，例如：外生破裂性變異型好發於兒童，水泡狀變異型好發於女性成人，以及擬似癌症變化則常見於老年人患者。故成人及老年人組需要考慮惡性腫瘤的可能性與非典型組織病理學的變化。治療該正手選為病灶切除手術，該症經由治療之後復發率極低。

關鍵字

眼瞼毛髮編織瘤；頭頸部毛髮編織瘤；水泡狀毛髮編織瘤

並列摘要

Background & Purpose: Pilomatricoma is a benign skin tumor arising from the hair matrix, which is generally recognized in children with female predominance, but rarely seen in male adults on the eyelid and eyebrow region. We reported a male adult with pilomatricoma beneath eyebrow and employed a literature review with much broader age range. Method: A case of report and a literature review among the three age groups, including children, adults and the elderly were employed. Results: Based on our case report and a literature review, the conclusions are drawn as follows: (1) Most of pilomatricomas occur in children with female predominance and rarely in male adults. (2) Typically clinical characteristics of pilomatricomas are solitary, asymptomatic, slowly growing, bony-hard, subcutaneous nodule. (3) Preoperatively, they are often missed diagnosis or differential diagnosis, of which accuracy ranged from 30 to 82%. (4) Pilomatricomas among the three age groups have shown almost the same on clinical characteristics, histopathological features and treatment outcome, except exophtic-perforan variants in children, anettodermal/bullous variants in female adults and mimicking malignant change in the elderly. (5) Most of cases are no recurrence after totally excision and biopsy. Conclusion: Careful clinical examination and high index of suspicion result in preoperatively accurate diagnosis, appropriate treatment and avoidnce of unnecessary management of male adults with pilomatricomas.

並列關鍵字

pilomatricoma of head ； pilomatricoma of eyelid ； pilomatrixoma ； pilomatric carcinoma ； bullous pilomatricoma

國際替代計量

Pilomatricoma of the Eyelid and Eyebrow in an Adult Male

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