Cytologic Findings of Cervicovaginal Smears in a Woman with Endometrial Clear Cell Carcinoma: A Case Report

子宮頸抹片中亮細胞子宮內膜癌的細胞學表現－病例報告

葉寶貴(Pao-Kuei Yeh) ； 黃純容(Chun-Jung Huang) ； 朱繼璋(Chi-Chang Chu) ； 黃佳雯(Chia-Wen Huang)

《北市醫學雜誌》 17卷3期 (2020/09) Pp. 338-342

https://doi.org/10.6200/TCMJ.202009_17(3).0008

摘要

Objective: Very few reports have described the cytological features of endometrial clear cell carcinoma (CCC). We report the cytomorphologic features of a case of endometrial CCC. Case report: A 59-year-old woman with no major past medical history participated in the routine cervical cancer screening in our hospital. The cervical cytology showed clusters of pleomorphic adenocarcinoma cells with high nuclear/cytoplasmic (N/C) ratio, vacuolated cytoplasm, distinct cell borders, round to oval centrally located nuclei, large nucleoli, and fine granular chromatins. Granular diathesis in the background was noted. Endometrial curettage revealed a picture of CCC. Conclusion: To be familiar with the presentation of cytologic features of endometrial CCC is helpful for earlier diagnosis before the symptoms and signs develop.

關鍵字

endometrial ； clear ； cytology

並列摘要

目的：描述子宮內膜亮細胞癌的細胞學表現的文獻很少，我們報告一個子宮內膜亮細胞癌個案的細胞學表現。病例報告：一位過去無重大病史的59歲婦女來院接受子宮頸抹片篩檢。在子宮頸抹片中觀察到成團的腺癌細胞。這些腫瘤細胞具有高核質比，空泡狀胞漿，明顯的細胞邊界，圓形或橢圓形位在細胞中央的核，大的核仁以及細顆粒的染色質。背景可見粒狀素質。子宮內膜刮除做病理切片檢查診斷為亮細胞癌。結論：孰悉子宮內膜亮細胞癌的細胞學表現將有助於在病人產生症狀與徵兆前及早發現腫瘤。

並列關鍵字

子宮內膜 ； 亮細胞 ； 細胞學