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摘要


失智症是一種奪取人們記憶等認知功能的症候群,包含認知功能的異常、記憶能力的逐漸退步及出現精神症狀。過去的研究顯示,慢性腎臟病患者罹患失智症的風險較高。雖然紅血球生成素與鐵劑的補充,常用於治療慢性腎臟病和末期腎衰竭所引起的貧血;紅血球生成素也具有神經保護作用,與認知功能的改善。在血液透析患者中使用紅血球生成素藥物可有效降低血管性及其它原因造成失智症的風險。因此,紅血球生成素可能有機會發展為血管性失智症的治療藥物,但仍有待更進一步的研究。

並列摘要


Dementia is a syndrome that seizes human memory and cognitive function, including cognitive abnormality, degeneration of memory, and the emergence of psychosis. Past studies have shown that individuals at all stages of chronic kidney disease (CKD) have a higher risk of developing cognitive disorders such as dementia. Besides, erythropoietin and iron are indicated to treat anemia in patients with CKD and end-stage renal disease. Erythropoietin is known to have neuroprotective effects and is correlated with improved cognitive functions. Interestingly, the use of erythropoietin medications in hemodialysis patients is associated with a reduced risk of vascular dementia and unspecified dementia. Thus, erythropoietin may have the opportunity to develop into a therapeutic drug for vascular dementia, and more research is needed.

被引用紀錄


洪姵如(2022)。當慢性腎衰竭遇上失智症彰化護理29(3),15-18。https://doi.org/10.6647/CN.202209_29(3).0004
楊舒雅(2022)。慢性腎臟病與失智症之探討彰化護理29(3),9-14。https://doi.org/10.6647/CN.202209_29(3).0003

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