臭氧氣體於呼吸器快速滅菌消毒之應用

目的：近年新興傳染病盛行，病菌透過人群間密切接觸及飛沫傳播，因此預防院內感染已成為近年重要的公共衛生議題。以近期的新冠肺炎為例，其引起肺炎的病人在治療時，常需要使用呼吸器，當需求提高時，需要有效方法來深度消毒使用過的呼吸器，以提高儀器使用效率。方法：本研究在平均環境濕度為66%下，使用臭氧生成機以約200ppm濃度之臭氧進行呼吸器內部消毒殺菌，檢測包括糞腸球菌（Enterococcus faecalis），抗藥性金黃色葡萄球菌（Staphylococcus aureus, MRSA），及大腸桿菌（Escherichia coli 25922）。結果：發現使用此濃度之氣態臭氧對於特定濃度菌落的三種細菌，60分鐘就可以達到90%以上的殺菌力。結論：經由本研究發現，高濃度氣態臭氧是有效的空氣消毒方法，注意使用安全，即可應用於呼吸器的快速深度消毒，確保病人安全並提高儀器使用效率。

關鍵字

病原菌；新冠肺炎病毒；臭氧；呼吸器

並列摘要

Objective: Emerging infectious diseases have become prevalent in recent years. These diseases are spread through close contact by respiratory droplets. Thus, preventing these nosocomial infections appears to be a significant public health issue in recent years. Patients with severe pneumonia caused by SARS-CoV-2 often need ventilators. When the demand for ventilators increases, a reliable and effective decontamination process is necessary to sanitize the used ventilators in deep to improve the use rate. Methods: This study used ozone gas at a concentration of approximately 200 ppm under an average environmental humidity of 66% to disinfect the interior of ventilators and measured the survival fraction of Enterococcus faecalis (E. faecalis), drug-resistant Staphylococcus aureus (S. aureus, MRSA), and Escherichia coli (E. coli). Results: We found that applying gaseous ozone for 60 minutes can achieve 90% bactericidal power for these three bacteria under specific colony inoculation conditions. Conclusion: This study found that high-concentration gaseous ozone is an effective air disinfection method. This protocol can be applied for rapid, deep disinfection of respirators to ensure patient safety and increase the ventilators' use rate, providing that safety is monitored.

並列關鍵字

microbial pathogen ； COVID-19 ； ozone ； ventilator

國際替代計量

臭氧氣體於呼吸器快速滅菌消毒之應用

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