影響系統性紅斑性狼瘡女性患者特定疾病生活品質的相關因子

目的：本研究旨在透過「狼瘡生活品質量表」（LupusQoL）探討女性系統性紅斑性狼瘡患者多面向的特定疾病生活品質及其相關因子。方法：本研究採用橫斷式問卷調查設計，於南部某區域醫院過敏免疫風濕中心收案，並以多變項線性迴歸分析與多變量變異數分析探討狼瘡生活品質量表八個構面的獨立顯著相關因子。結果：系統性紅斑性狼瘡顯著影響患者多方面的特定疾病生活品質，當中影響較大的為疲憊、為別人帶來負擔和親密關係的三個構面。在影響整體特定疾病生活品質的7項顯著相關因子中，使用安眠藥的效應最大（效果量淨相關η平方=0.14）。結論：本研究結果顯示，提升睡眠的質和量是改善系統性紅斑性狼瘡患者整體特定疾病生活品質的重點。

關鍵字

全身性紅斑性狼瘡；特性疾病生活品質；女性病人

並列摘要

Objectives: This study aimed to investigate various domains of quality of life and associated factors in women with systemic lupus erythematosus using the LupusQoL. Methods: A cross-sectional survey design was used to recruit patients at the rheumatology clinic of a regional hospital in southern Taiwan. Multivariate linear regression analysis and multivariate analysis of variance were used to explore the independent and significant factors associated with the eight domains of the LupusQoL. Results: Systemic lupus erythematosus significantly affected the disease-specific quality of life of the patients in various domains. The more affecting domains were fatigue, the burden on others, and intimate relationships. Among the seven significant related quality of life factors, sleep medication demonstrated the most robust effect (partial eta squared = 0.14). Conclusions: This study showed that improving the quality and quantity of sleep is crucial in enhancing the overall disease-specific quality of life in SLE patients.

並列關鍵字

systemic lupus erythematosus ； health-related quality of life ； quality of life ； survey

主題瀏覽