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感染後併發格林-巴瑞症候群:案例報告

Infection Complicated Guillain-Barre syndrome: A Case Report

摘要


格林-巴瑞症候群是急性、對稱性週邊神經發炎導致脫髓鞘疾病。三分之二患者在發病前曾出現感染特徵。本個案是一位46歲女性因B型流行性感冒一週後出現四肢無力合併呼吸喘的表現,經由理學檢查、神經電生理檢查及腦脊髓液檢查呈現典型表現,確診為格林-巴瑞症候群。給予第一劑免疫球蛋白治療立即出現過敏反應,故改為血漿置換術五次療程並配合復健治療,病情穩定出院。因此,當我們遇到個案於感染後發生急性雙側肢體無力,須高度懷疑格林-巴瑞症候群的可能性。

並列摘要


Guillain-Barre syndrome is an acute, symmetrical peripheral nerve inflammation that causes demyelinating disease.Two-thirds of the patients showed signs of infection before discase onset.This 46-year-old woman sufferred from paralysis in her extremities and shortness of breath a week after influenza B infection. Guillain-Barre syndrome was diagnosed as physical examination, neuroelectrophysiological study and cerebrospinal fluid analysis showed typical findings. An allergic reaction occurred immediately after the first dose of immunoglobulin injection. Therefore, five cycles of plasmapheresis was used instead combined with rehabilitation treatment. The patient had an uneventful stag and was subsequently discharged.Guillain-Barre syndrome should be kept in mind during future encompass of acute bilateral limb weakness after an infection.

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