The primary issue of the study is to exam the relationships among external relations integrations, supply chain risk, and open innovation impaction supply chain performance. In addition, we further examine the role of moderating of open innovation and value co-creation in above-mention relationships. Through a large-scale survey, we finding that: the extend of external relationship integration of supply chain has positive effects on supply chain performance; supply chain performance is negatively affected by supply chain risk; open innovation and value co-creating can significantly bring positive moderating effects on the relationship between external relationship integration and supply chain performance; open innovation and value co-creating cannot mitigate the negative effect of supply chain risk.