迪喬氏症候群患者的牙科治療考量－病例報告

Dental Consideration for the Treatment of Patient with DiGeorge syndrome - A Case Report

吳富雅(Fu-Ya Wu) ； 施文宇(Wen-Yu Shih)

《臺灣兒童牙醫學雜誌》 17卷4期 (2017/12) Pp. 149-153

https://doi.org/10.6319/TJPD.2017.17(4).0003

摘要

迪喬氏症候群又稱為22q11.2缺失症候群，新生兒發生率為1/4,000~1/5,000。全身性疾病包含先天性心臟病、免疫功能不佳、顎裂以及低血鈣等。而發展遲緩伴隨行為與情緒障礙也常出現。此病童的年齡為3歲10個月，出現的症狀包含骨骼和牙齒的異常、高顎弓、小嘴巴、開咬以及低張力的口腔周圍肌肉。這次前來求診的原因是早期兒童齲齒及牙齦炎。迪喬氏症候群包含許多症狀會影響我們的治療計畫和執行，例如顎裂、低血鈣和先天性心臟病等等，因此除了定期的牙科回診追蹤外，我們還必須教導病患客製化的飲食習慣和如何維持良好的口腔衛生。如此一來才有機會降低齲齒和感染的風險。

關鍵字

迪喬氏症候群 ； 早期兒童嚴重齲齒 ； 牙釉質發育不全或礦化不全

並列摘要

DiGeorge syndrome, also called 22q11.2 deletion syndrome, has an incidence of approximately 1:4,000 to 1:5,000 live births. Medical problems commonly associated with DiGeorge syndrome include congenital heart disease, poor immune system function, cleft palate, complications related to low levels of calcium in the blood, and delayed development with behavioral and emotional problems. This case presented is a 3Y10M old boy who was diagnosed with DiGeorge syndrome. Dental aspects in this patient include skeletal malformations, tooth-related deformities, high palatal vault, small mouth, open bite, and hypotonus orofacial musculature. He visited our department because he was suffered from severe early childhood caries and gingivitis. DiGeorge syndrome involves many aspects, which may influence our dental treatment planning, and management, such as cleft palate, low level of calcium, and congenital heart disease. Therefore, in addition to regular dental recall, educating patients' gardiants on strict oral hygiene maintenance and individual diet instructions is more important to reduce the risk of extensive carious lesions and odontogenic infection.

並列關鍵字

DiGeorge syndrome ； severe early childhood caries ； enamel hypoplasia or hypomineralization