Sinosenecio sichuanicus Y. Liu & Q. E. Yang, a new species from Sichuan, China, is described and illustrated. The new species is similar to S. chienii (Hand.-Mazz.) B. Nord. in the leaf shape and the mature achenes usually epappose, but differs by having 2-3 cauline leaves, the leaf-lamina pubescent on both surfaces, the petioles pubescent, and the rays larger, 18-20 × 4-5 mm. Its somatic chromosome number (2n = 60) is reported here. Photographs of both S. sichuanicus and S. chienii, line drawings, distribution map, and light microscope (LM) microphotographs of floral characters of S. sichuanicus are provided.