Retarding renal progression in patient with diabetes remains a big challenge for Western medicine. One 59-year-old male patient with extreme low renal function (estimated glomerular filtration rate: 6 ml/min/1.73 m^2) visited our hospital admission due to hypoglycemia. The holistic differential diagnosis was Spleen-Kidney Yang Deficiency. Acupuncture treatment was suggesting regular given during this admission and subsequent outpatient visits. After needle stimulating 7 vital acupuncture points (Zhongwan, Guanyuan, Shenshu, Zusanli, Taixi , Weizhong, and Sanyinjiao), patient renal function and proteinuria had significantly improved. Our results encourage more integrated Western and Chinese medicine care in improving patient outcomes and strengthen the rationality and justification of acupuncture on disease management.