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“脾主肌肉”理论的现代研究与展望

Modrn Research and Development of the Theory of the Spleen Governs the Musile

摘要


通过结合“脾主肌肉”学说研究领域涉及古代文献与现代研究资料的回顾梳理与分析,从探讨其理论渊源与沿革、现代基础与临床研究进展、临床治疗现状等方面进行了归纳,进一步确定了该理论的临床指导意义,同时揭示“脾主肌肉”的理论基础主要体现在肌肉的运动与能量代谢两方面。脾虚则肌肉不得所主包含肌肉运动功能障碍出现的痿废不用和能量代谢异常所致的肌肉消瘦,营养不良等,结合现代分子生物学进展,创新性提出“解耦连蛋白可能成为‘脾主肌肉’理论研究新的生长点”,为今后的研究提供新的领域与发展的思路。

關鍵字

脾主肌肉 脾虚 解耦连蛋白

並列摘要


By combining the ancient doctrine of research and the modern journal literature involved ”the spleen governs the muscles” theory to analysis the origin and evolution of the theory, modern basic and clinical research, clinical treatment and other aspects of the status quo are summarized, and further defined the theory of clinical significance, at the same time revealed the theoretical basis for spleen governing the muscles mainly based on two aspects including muscle movement and energy metabolism. Spleen deficiency contributing to muscle monitoring dysfunction also included 2 aspects. One is muscle atrophy and the other is dysfunction of energy metabolism causing muscle wasting, malnutrition, etc., and combined with modern molecular biology, innovatively proposed ”uncoupling proteins may be new growth theory of 'spleen governs the muscles'”, which will provide for future research and development in new areas.

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