This article introduces the concept of translational research and its relationship with quality improvement. Translational research has become the trend of national medical research with the purpose to promote evidence into the clinical field to enhance the quality of care. Various types of nursing research activities have been conducted; however, the findings were seldom applied in clinical practice. Suggestions will be made on how to prepare nurses in the application of research evidence into bedside nursing. The ultimate goal is to closely connect the translational research and quality improvement.