睫狀體冷凍治療新生血管性青光眼的長期結果

Long-term Outcome of Cyclocryotherapy for Neovascular Glaucoma

樊文雄(Wen-Shuang Fan) ； 張璟育(Ching-Yu Chang)

《南臺灣醫學雜誌》 1卷1期 (2006/06) Pp. 51-56

https://doi.org/10.6726/MJST.200606_1(1).0007

摘要

Purpose: To determine the long-term efficacy and safety of cyclocryotherapy for the treatment of neovascular glaucoma.Methods: Retrospective, non- comparative, interventional case series. 21 eyes of 20 subjects treated from September 2000 to September 2005. Eyes with un-controlled NVG underwent cyclocryo-therapy. Pre-treatment and post-treatment intraocular pressures, neovasculization, visual acuity, pain scores and complications were reviewed. Criteria for success in-cluded intraocular pressure (IOP) of 21 mmHg or less, in the absence of phthisis or need for further surgical procedures. Results were subjected to a Kaplan-Meier life-table analysis.Results: Mean follow-up was 22.62 ± 15.24 months (range, 6-53). Mean preoperative IOP was 51.67± 8.46mmHg (range, 30-60). Mean postoperative IOP was 16.62 ± 9.82.2 mmHg (range, 5-40). Pain scores decreased from 2.62± 0.50 to 0.62 ± 0.74 in the first postoperative month. Kaplan-Meier survival analysis showed a probability of continued success at 1 year of 82.0%, at 2 years of 82.0 %, at 3 years of 70.3%, at 4 years of 46.8%, and at 5 years of 46.8%. Phthisis or hypotony developed in 9.52% of the eyes.Conclusions: Cyclocryotherapy is an effective means of lowering IOP and relieving pain. This can be associated with complications that include inflammation, visual loss, and hypotony. There are two key aspects to the management of NVG: treatment of the underlying disease process responsible for rubeosis and treatment of the increased IOP. In patients with opaque media, panretinal cryopexy combined with 180 degree cyclocryotherapy is a reasonable treatment option.

關鍵字

新生血管青光眼 ； 睫狀體冷凍治療 ； 後遺症

並列摘要

Purpose: To determine the long-term efficacy and safety of cyclocryotherapy for the treatment of neovascular glaucoma.Methods: Retrospective, non- comparative, interventional case series. 21 eyes of 20 subjects treated from September 2000 to September 2005. Eyes with un-controlled NVG underwent cyclocryo-therapy. Pre-treatment and post-treatment intraocular pressures, neovasculization, visual acuity, pain scores and complications were reviewed. Criteria for success in-cluded intraocular pressure (IOP) of 21 mmHg or less, in the absence of phthisis or need for further surgical procedures. Results were subjected to a Kaplan-Meier life-table analysis.Results: Mean follow-up was 22.62 ± 15.24 months (range, 6-53). Mean preoperative IOP was 51.67± 8.46mmHg (range, 30-60). Mean postoperative IOP was 16.62 ± 9.82.2 mmHg (range, 5-40). Pain scores decreased from 2.62± 0.50 to 0.62 ± 0.74 in the first postoperative month. Kaplan-Meier survival analysis showed a probability of continued success at 1 year of 82.0%, at 2 years of 82.0 %, at 3 years of 70.3%, at 4 years of 46.8%, and at 5 years of 46.8%. Phthisis or hypotony developed in 9.52% of the eyes.Conclusions: Cyclocryotherapy is an effective means of lowering IOP and relieving pain. This can be associated with complications that include inflammation, visual loss, and hypotony. There are two key aspects to the management of NVG: treatment of the underlying disease process responsible for rubeosis and treatment of the increased IOP. In patients with opaque media, panretinal cryopexy combined with 180 degree cyclocryotherapy is a reasonable treatment option.

並列關鍵字

neovascular glaucoma ； cyclocryotherapy ； complications