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自體纖維蛋白原濃縮物於治療青光眼手術後低眼壓症之運用―病例報告
The Use of Autologous Fibrinogen Concentrate in Treating Hypotony Patient after Glaucoma Filtration Surgery-Case Report
摘要
本文報告兩例應用自體纖維蛋白原濃縮物(Autologous fibrinogen concentrate)治療青光眼手術後低眼壓症之病例，病人分別為二十一歲及二十三歲男性，診斷皆為雙眼原發性偶角開放型青光眼，並於民國八十七年三月及八十七年七月，分別接受右眼及左眼青光眼小樑切除術（以下稱手術眼為患眼），並在術中使用mitomycin-C 0.4mg/ml浸泡約一分鐘，術後兩週兩患者皆發生息眼低眼壓症及前房狹窄、網膜黃斑部病變及視力減退等併發症，由於保守療法無效，為改善患者之狀況，兩名患者皆接受經由結膜下注射自體纖維蛋白原濃縮物及凝血酵素(Thrombin)治療，患眼眼壓於兩日後逐漸上升，黃斑部水腫及視力約兩週後亦逐漸恢復，吾人藉向應用自體纖維蛋白原濃縮物，治療青光眼術後低眼壓症之臨床經驗來探討其安全及有效性。
關鍵字
無資料並列摘要
We presented the experience of treating hypotony after glaucoma filtering surgery in two young myopic male. They underwent trabeculectomy with intraoperative mitomycin-C in their right eye and left eye on March and July, 1998, separately. Two weeks after filtering surgery, shallow anterior chamber, iridocorneal touch and hypotonous maculopathy developed and visual acuity dropped down dramatically. After subconjunctival injection of autologous fibrinogen concentrate with thrombin was performed, the intraocular pressure elevated and anterior chamber became deep on the second day. Two weeks later, macular edema and visual acuity improved gradually. It was found that autologous fibrinogen concentrate appeared to be safe and effective for the repairment of excessively draining bleb after filtering surgery.
延伸閱讀
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