12週跑走對坐式生活者血液生化、抗氧化能力及壓力指標之影響

目的：坐式生活型態誘發心血管等疾病發生的機制可能與氧化壓力的增加有關，而藉由規律運動的介入可以調控生理功能、增加抗氧化能力且促進人體的健康。本研究旨在探討12週跑走運動訓練對坐臥式生活者之血液生化值、抗氧化能力及壓力指標水準有何影響？方法：受試者為9位坐式生活健康男性大學生（年齡19.90±1.17歲，身高176.43±6.51公分，體重68.78±9.61公斤），自願接受每週3次，每次30分鐘，持續12週的跑走運動訓練。運動強度以運動自覺量表（rating of perceived exertion, RPE）為依據，實施數值為12-14跑走運動。研究設計採前實驗設計（pre-experimental design）中的單組前、後測設計（single-group pretest-posttest design）方法。受試者在運動前、後休息48小時，抽上臂靜脈血10毫升進行生化值、穀胱甘肽（Glutathione, GSH）、過氧化氫酶（Catalase, CAT）及脂質過氧化－硫代巴比妥酸（thiobarbituric acid-reactive substances, TBARS）等濃度分析。結果：訓練後血液生化值血紅素濃度（13.98±1.13g/dL）較高於訓練前（12.67±1.33g/dL），達顯著水準。而尿氮素（blood urea nitrogen, BUN）的結果，訓練後（11.38±1.74mg/dL）比訓練前（13.4±01.60mg/dL）有顯著的下降；穀胱甘肽和過氧化氫酶指標在練後測亦有明顯的上升。此外，代表壓力荷爾蒙指標的可體松濃度，則是在長期運動後有顯著性的下降。結論：每週3次，每次30分鐘，持續12週的跑走運動能有效提升抗氧化能力，並減少壓力荷爾蒙指標水準。

關鍵字

規律有氧運動；抗氧化能力；穀胱甘肽；可體松

並列摘要

Purpose: A sedentary lifestyle is easy to induce cardiac related diseases and related with oxidative stress. As we known, regular exercise could promote the health and enhance the antioxidant capacity. The purpose of this study is to investigate the effects of 12 weeks moderate aerobic running/walking program on levels of serum biochemical parameters, antioxidant capacity and stress hormones in the sedentary men. Methods: Nine sedentary and healthy subjects (age 19.9±1.17 years) without any acute or chronic inflammatory diseases were recruited to participate in this study. All the participants will be instructed to perform a 12 weeks aerobic running/walking plan and 30 minutes every time at least three times per week in the late afternoon. Rating of Perceived Exertion (RPE; 12-14 score) was used to subjectively quantify an individual's perception of the exercise intensity. The blood biochemical parameters, levels of antioxidant capacity, lipid peroxidation and cortisol concentration would be assessed before training plan and after 12 weeks program. Results: To compare the before exercise with after exercise, this study revealed that hemoglobin concentration were significantly increased and BUN was meaningfully reduced. The levels of GSH and CAT were notedly augmented. TBARS of LPO index was no difference. Besides, the stress hormone of cortisol concentration was significantly decreased after the 12 weeks running/walking project. Conclusion: Moderate intensity and 30mins aerobic running/walking plan for 12 weeks at least three times per week may effectively promote the antioxidant capacity and reduce the level of cortisol.

並列關鍵字

Regular exercise ； antioxidant capacity ； GSH ； cortisol

參考文獻

潘正德（2004）。壓力管理。臺北市：心理。

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