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Utilizing Pulse-Derived Heart Rate Parameter to Estimate the Risk of Iodinated Contrast Medium under Computer Tomography Examination

並列摘要


Intravenous iodinated contrast medium (ICM), an important medium to enhance computer tomography (CT) examination images, may cause palpitation, emesis, stress phenomena, and even death to patients. The purpose of this study is to develop a real-time risk monitoring system for patients under CT examination. Thirty eight patients were selected. The risk monitoring system was based on the heart rate variation. To obtain the heart rate information, the pulse wave data during ICM injection were measured and followed by using moving average filter twice and peak detection algorithms. Patients were divided into two groups based on their discomfort index. There are statistical differences between the two groups in heart rate derived parameters after ICM injection, especially in the cumulated heart rate deviation (CHRD). The CHRD increases steadily after ICM injection, and patients with higher discomfort index have higher CHRDs. CHRD is an effective parameter of an early warning indicator within two minutes after ICM injection (p<0.003(superscript **)). However, the current medical procedure takes nearly thirty minutes to decide whether the patients are extremely uncomfortable and need further medical treatments.

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