- 期刊
- OpenAccess
The Effect of Flunixin Injection on Reproductive Hormones in Male Mice
並列摘要
Flunixin is an anti inflammatory non steroidal chemical compound which is used as an analgesic and antipyretic drug in veterinary. Considering the frequent use of this drug in recent years this study was conducted to investigate the effects of this drug on pituitary-gonad axis of male mice. Results of this study can be used highly for better use of this drug and saving sexual power of male sex. Five experimental groups with eight male mice in each group were studied as control, Placebo and three treatment groups. Flunixin was injected in 0.5, 1 and 1.5 mg/kg in peritoneum in a twenty-day period. Control group didn't receive any injection and Placebo group received only physiological serum. At the end of twenty days, blood samples were prepared and the amounts of FSH, LH and testosterone hormones were measured. Obtained data were analyzed using SPSS11.5 program. According to results, FSH and LH concentrations were increased significantly (p＜0.05) but testosterone was not changed. Results show that flunixin can affect sexual power of male sex by increasing hormones of pituitary-testicle axis.
延伸閱讀
- Wu, J. H. (2011). The effects of male pheromones on adult neurogenesis in the accessory olfactory bulb of female mice [master's thesis, National Taiwan Normal University]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0021-1610201315244316
- Pi, W. P., & Lin, C. H. (1993). Effects of Monoamine Precursors on Food Intake in Male Rats. The Chinese Journal of Physiology, 36(3), 171-176. https://www.airitilibrary.com/Article/Detail?DocID=03044920-199309-36-3-171-176-a
- Kuo, Y. F., & Fang, H. S. (1967). Effect of Some Vitamins on Resistance to Hypoxia in Mice. The Chinese Journal of Physiology, 20(1), 79-82. https://www.airitilibrary.com/Article/Detail?DocID=03044920-196706-20-1-79-82-a
- Sedigh, A., Modaresi, M., & Pirestani, A. (2014). Effect of Organic and Mineral Zinc Supplement in Diet on Reproductive Hormones in Mice. International Journal of Animal and Veterinary Advances, 6(2), 77-79. https://www.airitilibrary.com/Article/Detail?DocID=20412908-201404-201507200027-201507200027-77-79
- Ko, M. C. (2010). Effects of Neonatal Fluoxetine Exposure on the Serotonergic System of Rats [master's thesis, National Taiwan University]. Airiti Library. https://doi.org/10.6342/NTU.2010.01188