頸部淋巴節之濾泡樹突狀細胞肉瘤：病例報告

Follicular Dendritic Cell Sarcoma of Cervical LN: Case Report

楊振楠(Chen-Nan Yang) ； 呂宗禧(Tsung-His Lu) ； 蔡宜璋(Yi-Chang Tsai) ； 葉文堯(Wu-Yan Yen)

《童綜合醫學雜誌》 2卷1期 (2008/06) Pp. 57-61

https://doi.org/10.29838/TMJ.200806.0010

摘要

濾泡樹突狀細胞肉瘤（Follicular dentritic cell sarcoma）為一罕見之惡性腫瘤，自Monda氏於1986年提出首例後，至目前為止文獻上約有70餘例病例報告。好發部位以頸部淋巴結為主，但淋巴結外組織亦可發生。本病例為17歲男性病患、主訴發現右側頸部無痛性腫塊約2個月，並曾有輕微感冒症狀。理學檢查為可動性無痛性右頸部腫塊，約4 cm大小。頸部電腦斷層掃瞄下所見，除右頸腫塊，並無其他部位病灶。病患接受腫瘤切除式手術後，根據其臨床表現、組織學形態、免疫組織化學染色結果，診斷為濾泡樹突狀細胞肉瘤。濾泡樹突狀細胞肉瘤為一中度惡性腫瘤，治療以廣泛性手術切除為主，術後輔助性放射線及化學治療有助於腫瘤的控制。

並列摘要

Follicular dendritic cell sarcoma (FDCS), first described in 1986 by Monda, is a rare type of malignancy and thus far, more then 70 cases have been documented in the literature. FDCS is frequently occurred at cervical lymph node, but other extra-nodal locations can also be seen. Here, we report a case of cervical FDCS. This patient, a 17-years old adolescent, was originally presented with a painless nodule at the right neck for 2 months. He underwent surgical excision and based on microscopic findings and immunohistochemistry results, he was diagnosed to be a case of FDCS with two poor prognostic factors. The patient was subsequently received adjuvant radiotherapy. During the follow-up period of 20 months, there have been no signs of recurrence. Together, we suggest that the proper treatment for a moderately aggressive FDCS should include wide excision and post-operative adjuvant chemotherapy or radiotherapy.

並列關鍵字

follicular dendritic cell sarcoma ； neck malignancy ； immunohistochemistry ； CD21 ； CD35