Adrenal Cortical Carcinoma: A case report and literature review

腎上腺皮質癌：一病例報告及文獻回顧

殷約翰(Jue-Hawan Yin) ； 許兆畬(Zhon-Min Huang) ； 曹唐義(Tang-Yi Tsao)

《童綜合醫學雜誌》 9卷2期 (2015/12) Pp. 142-145

摘要

一位72 歲女性有高血壓病史大約6 年時間，並且在門診持續追蹤治療。病人抱怨最近5個月左上腹部會痛。門診腹部超音波檢查發現在左腎上腺有一5.6公分的腫塊，核磁共振檢查發現在左腎上腺有一5.4 x 4.5公分加強顯影的腫塊，中央部分有壞死現象。在臨床診斷為腎上腺嗜鉻細胞瘤下，病患接受經腹腔鏡達文西機械手臂協助左腎上腺腫瘤切除手術。依據Weiss 顯微鏡下診斷條件以及免疫染色的結果）Melan A+, synaptophysin+ and chromogranin-），最後病理診斷為腎上腺皮質癌。腎上腺皮質癌是腎上腺皮質非常少見的惡性腫瘤，於此我們報告一病例並且做一文獻回顧。

關鍵字

腎上腺皮質癌 ； 腎上腺嗜鉻細胞瘤

並列摘要

A 72-year-old female with hypertension received regular treatment at our cardiovascular outpatient department. After six years of treatment, she complained of left upper quadrant abdominal pain that had been occurring occasionally for five months. Sonography of the abdomen revealed a 5.6 cm left suprarenal mass. Furthermore, magnetic resonance imaging showed a large irregular heterogeneous left adrenal enhanced mass, measuring approximately 5.4 × 4.5 cm with central necrosis. Based on suspected pheochromocytoma, daVinci robotic-assisted laparoscopic en bloc resection of the left adrenal tumor was performed. Diagnosis of stage I (≤5 cm) adrenal cortical carcinoma (ACC) was made based on microscopic diagnostic criteria of Weiss score along with immunohistochemical stain findings (positive for Melan A and synaptophysin and negative for chromogranin). ACC is a rare malignant adrenal cortex tumor. Here we report an ACC case and review the literature.

並列關鍵字

Adrenal cortical carcinoma ； pheochromocytoma