Clinical Observation on Lumbar Paravertebral Injection of Oxygen-Ozone Combined with Functional Exercise in the Treatment of Lumbocrural Pain with Degenerative Lumbar Spondylolisthesis in Old People

Juan-Hong Li ； Gui-Ying Li ； Bin Cheng ； Yi-Ying Zhu

《台灣老年醫學暨老年學雜誌》 9卷2期 (2014/05) Pp. 56-56(2)

並列摘要

Objective: To assess the clinical effects of treating elderly degenerative lumbar spondylolisthesis suffering from lumbocrural pain by lumbar paravertebral injection of oxygen-ozone combined with lumbar functional exercise. Methods: A prospective, randomized, controlled clinical trial was carried on 77 elderly patients suffering from lumbocrural pain caused by degenerative lumbar spondylolisthesis during Mar 2010 to May 2011. All patients were divided with the random number table method into three groups, lumbar paravertebral injection of oxygen-ozone combined with lumbar functional exercise group (ozone-grp), lumbar paravertebral injection of 0.5% lidocaine combined with lumbar functional exercise group(local-blok-grp) and single lumbar functional exercise group (control-grp). All groups performed lumbar functional exercise of rolling and rotating maneuvers with hip and knee flexion. The local-blok-grp also received lumbarparavertebral injection of 0.5% lidocaine at the same period for 4 to 6 times (once a week). The ozone-grp received lumbar paravertebral injection of 0.5% lidocaine and oxygen-ozone at the same period for 4 to 6 times (once a week). The improvement of clinical symptoms were assessed with VAS for waist pain, the lower limb pain VAS and the lumbar JOA score. Results: A total of 68 patients completed the full 1-year follow up. The VAS for ozone-grp were significantly lower than that for control-grp and local-blok-grp at 1 week and 1 month after treatment (P ＜ 0.05). There was no significant difference in VAS scores at 1 week and 1 month between local-blok-grp and control-grp (P ＞ 0.05). The VAS scores for ozone-grp were significantly lower than for control-grp and local-blok-grp at 1 year after treatment (P ＜ 0.05). For the three groups, the intragroup comparisons of VAS scores at 1 year after treatment and before showed statistically significant differences (P ＜ 0.05). According to the results of lumbar JOA scores after the treatment, the total effective rate for ozone-grp were higher than for control-grp and local-blok-grp(P ＜ 0.05). The average duration of painkiller medicine use for ozone-grp was 5.23±1.78 days, significantly shorter than those for controlgrp (13.68±5.18 days) and local-blok-grp (18.76±7.57 days (P ＜ 0.05). Conclusion: The therapy of lumbar paravertebral injection of oxygen-ozone combined with functional exercise for elderly degenerative lumbar spondylolisthesis is safe, effective, and worthy of clinical promotion.