Free Cancer Cells Detection in Surgical Field Washings of Breast Cancer

Meng-Yao Sun ； Kai Zhang ； Wen-Jun Liu ； Ya-Zhou Cui ； Jing-Zhong Sun ； Jian-Li Wang ； Rong Ma

《Adaptive Medicine》 5卷4期 (2013/12) Pp. 196-198

https://doi.org/10.4247/AM.2013.ABD061

並列摘要

Free cancer cells in the surgical field might be one of the causation of local recurrence in breast cancer patients who underwent mastectomy. The goal of the study was to provide a theoretical basis for killing or removing of the free cancer cells in the surgical field. Cytological examination of surgical field washings was performed in 148 patients with breast cancer. The results and pathological stages were compared and analyzed. Free cancer cells were found in the surgical field washings in 54 cases. The total positive rate of cytology was 37.8% (54/143). There was a significant relationship between the pathological stage, tumor size, axillary lymph node metastases and the positive rate of cytology, but no association with operation type was observed. Stage I, II and III showed a positive rate of 8.6%, 33.8% and 85.7%. The positive rate of T1, T2 and T3 plus T4 were 16.0%, 33.8% and 77.4%, respectively. When the number of axillary metastatic lymph nodes was over three, the positive rate of free cancer cells was 87.0% and only 20.1% if no axillary lymph node metastasis. Our study results suggested that killing or removing of the free cancer cells in the surgical field of breast cancer might be necessary during the operation.

並列關鍵字

breast cancer ； cytology ； free cancer cell ； surgical field