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Filamentous Structure of Cytidine Triphosphate Synthase

並列摘要


Nucleotide biosynthesis is a highly regulated process essential for cell growth and replication. Cytidine triphosphate synthase (CTPsyn) is a metabolic enzyme that catalyzes the rate-limiting step of de novo CTP biosynthesis. In addition to being an essential nucleotide, CTP is a basic building molecule (or block) of RNA, DNA, and phospholipids. Recently, CTPsyn was independently revealed to have a filamentous structure in bacteria, budding yeast, Drosophila, and mammalian cell lines, indicating that its structure is highly evolutionarily conserved. In the present review, we briefly discuss recent findings and suggest that future studies investigating the biological effect of the polymeric structure of CTPsyn will be expected.

並列關鍵字

CTPsyn cytoophidia filamentous structure IMPDH

被引用紀錄


張詩汎(2005)。在低溫環境下利用間接接合法將氮化銦及矽晶圓結合〔碩士論文,國立臺北科技大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0006-0507200515043000
鄭博元(2012)。高反射低電阻銀鑭合金P型氮化鎵歐姆接觸之研究〔碩士論文,國立中央大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0031-1903201314451581

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