- 期刊
- OpenAccess
No Perioperative Pulmonary Complications after Restricted Oxygen Exposition in Bleomycin-Treated Patients: A Short Report
並列摘要
Hyperoxic exposure during general anaesthesia after receiving bleomycin treatment is purported to potentiate bleomycininduced pulmonary toxicity. The aim of this study was to retrospectively assess perioperative pulmonary complications after general anaesthesia for retroperitoneal lymphadenectomy in patients who underwent bleomycin treatment ＜6 months earlier. A consecutive series of 47 patients who underwent surgery after bleomycin treatment were reviewed. Anaesthesia was induced with an inspired fraction of oxygen (FiO2) of 100% for 3 minutes and pertained with a FiO2 just under 30% throughout the procedure. We assessed all potential risk factors for bleomycin-induced pulmonary toxicity. Clinical signs for pulmonary damage were documented preoperatively (dyspnea, tachypnea, nonproductive cough, and postoperative oxygen saturation problems). No pathognomic clinical signs for pulmonary damage were detected up to 7 days postoperatively. Administration of 100% oxygen for 3 minutes during induction of anaesthesia and maintaining a FiO2 ＜ 30% during surgery was safe.
並列關鍵字
無資料延伸閱讀
- 李俊年、陳曉宜、蘇千玲、黃卓禕、許翰琳、江玲玲（2010）。The Efficacy of Oxygen Adjuncts to Exercise Training and Ambulation for Patients with Chronic Obstructive Pulmonary Disease。呼吸治療，9(1)，63-73。https://doi.org/10.6269/JRT.2010.9.1.07
- Karauzum, K., Karauzum, I., Kilic, T., Sahin, T., Baydemir, C., Argun, S. B., Celikyurt, U., Bildirici, U., & Agir, A. (2018). Bendopnea and Its Clinical Importance in Outpatient Patients with Pulmonary Arterial Hypertension. Acta Cardiologica Sinica, 34(6), 518-525. https://doi.org/10.6515/ACS.201811_34(6).20180528A
- Yen, C. C., Liu, K. Y., & Hsi, H. C. (2008). Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome in Trauma Patients: Case Report. 南臺灣醫學雜誌, 4(3), 140-145. https://doi.org/10.6726/MJST.200812_4(3).0003
- 林惠釧、許重梅、謝慧觀（2011）。Respiratory Care Experience of Pneumonectomy and Exacerbation of Chronic Obstructive Pulmonary Disease Cases。呼吸治療，10(2)，43-56。https://doi.org/10.6269/JRT.2011.10.2.04
- Gille, J., Seyfarth, H. J., Gerlach, S., Malcharek, M., Czeslick, E., & Sablotzki, A. (2012). Perioperative Anesthesiological Management of Patients with Pulmonary Hypertension. Anesthesiology Research and Practice, 2012(), 73-88. https://doi.org/10.1155/2012/356982