The purpose of this research was to explore the different status of depression on leisure satisfaction, life style and life satisfaction of older adults in Tainan city area as subjects and using survey instruments for data collection, 400 surveys were distributed and 334 valid surveys were returned for a rate of 83.5%. The returned data was analyzed by MANOVA. The results showed that the different status of depression had a significant difference on dimension of leisure satisfaction, which included psychological, social, physical, educational, relaxation, aesthetic, and overall leisure satisfaction. The different status of depression had a significant difference on dimension of life satisfaction, which included actualization, daily activity, and overall life satisfaction. However, there had no significant difference existed between the different status of depression and each dimension of life style.