Herpes zoster is a latent disease, an opportunistic viral infection, and is prone to appear in immunocompromised patients. The pain is unbearable and affects daily life. The prevalence of postherpetic neuralgia increases with age and severity of symptoms, which can persist for months or even years, so early treatment can reduce pain and improve quality of life. This 75-year-old female patient had herpes on her left upper face with cramping pain for more than 20 days, and it was repeated after routine western medicine treatment. After consultation with TCM syndrome differentiation and treatment, the symptoms were relieved and the quality of life improved after the combined use of acupuncture and medicine.