This article introduced the measures taken to guide students with disabilities by the resource room in National Formosa University, including the establishment of close-knit guidance network, the guidance of transitioning from high school to higher education for students with disabilities, the learning guidance, the interpersonal relationship building, the career and life planning, and the transition to workplaces. This article is written in the hope of inspiring more sharing of guidance experience among school counselors from college resource rooms and providing references for novice school counselors. In addition, this article is expected to help the senior/vocational high school students with disabilities, their parents and personnel concerned to know more about the services offered in college resource rooms.