一氧化氮對肌腱損傷復健的影響

The Effect of Nitric Oxide on Rehabilitation of Tendon Injury

楊昌斌(Chung-Pin Yang) ； 黃偉婷(Wei-Teng Huang) ； 林嘉志(Chai-Chih Lin) ； 謝伸裕(Shen-Yu Hsieh)

《大專體育學術專刊》 92年度 (下) (2003/06) Pp. 577-589

https://doi.org/10.6695/AUES.200306_92.0126

摘要

Fast recovery is very important for athlete with sports injury. However, traditional method of rehabilitation usually takes a long time. The purpose of this study was to shorten the treatment process. Twenty-four rats were randomly assigned into 4 groups: control with exercise, control without exercise, SNP (sodium niroprusside, a NO donor) treatment with exercise, SNP treatment without exercise. At the beginning, rat's Achilles tendon was cut off completely followed by exercise rehabilitation or NO donor treatment after the 3rd day of surgery. The following 19 days, the rehabilitation modality was swimming for 15 minutes per day and Achilles Function Index (AFI) was used to assess the recovery of Achilles tendon function. The difference between groups was analyzed by independent two-way ANOVA (SAS 8.0) and significant difference was set atα=.05. The data of AFI were shown as followed (mean ± SD): SNP treatment with exercise group (-0.6 ± 3.2), SNP treatment without exercise group (-6.3 ± 2.7), control with exercise group (-13.7 ± 4.2), control without exercise group (-26 ± 3.2). The results indicated that the AFI of SNP treatment with exercise group was significantly higher than that of control without exercise group and that of SNP treatment without exercise group. Conclusion: SNP treatment combined with swimming can promote the recovery of tendon injury.

關鍵字

運動復健

並列摘要

Fast recovery is very important for athlete with sports injury. However, traditional method of rehabilitation usually takes a long time. The purpose of this study was to shorten the treatment process. Twenty-four rats were randomly assigned into 4 groups: control with exercise, control without exercise, SNP (sodium niroprusside, a NO donor) treatment with exercise, SNP treatment without exercise. At the beginning, rat's Achilles tendon was cut off completely followed by exercise rehabilitation or NO donor treatment after the 3rd day of surgery. The following 19 days, the rehabilitation modality was swimming for 15 minutes per day and Achilles Function Index (AFI) was used to assess the recovery of Achilles tendon function. The difference between groups was analyzed by independent two-way ANOVA (SAS 8.0) and significant difference was set atα=.05. The data of AFI were shown as followed (mean ± SD): SNP treatment with exercise group (-0.6 ± 3.2), SNP treatment without exercise group (-6.3 ± 2.7), control with exercise group (-13.7 ± 4.2), control without exercise group (-26 ± 3.2). The results indicated that the AFI of SNP treatment with exercise group was significantly higher than that of control without exercise group and that of SNP treatment without exercise group. Conclusion: SNP treatment combined with swimming can promote the recovery of tendon injury.

並列關鍵字

NO ； SNP ； rehabilitation exercise