個案研究：中強度運動訓練對E抗原陽性之慢性B型肝炎帶原者肝功能之影響

Case Study: The Effects of Moderate Intensity Exercise to Liver Function of E-Antigen Positive Chronic Hepatitis B Carrier

林文煌(David Wen-Huang Lin)

《大專體育學術專刊》 93年度 (2004/05) Pp. 360-366

https://doi.org/10.6695/AUES.200405_93.0039

摘要

本研究目的在探討中強度運動訓練對e抗原陽性之慢性B型肝炎帶原者肝功能的影響。受試者為志願參與本研究e抗原陽性之慢性B型肝炎帶原者之男性1名，中強度運動訓練為心跳率130-140次/分，每週進行3次，每次30分鐘，連續進行12週。血液樣本於訓練前（T2）、訓練4週後（T2）、訓練8週後（T3）及訓練12週後（T4）採集，以分析包括直接型膽紅素（direct bilirubin）、總膽紅素（total bilirubin）、草醢乙酸轉胺酶（aspartate transaminase; AST）、丙酮酸轉胺酪（alanine transaminase; ALT）、鹼性磷酸酶（alkaline-phosphatase; Alk-p）、總蛋白（total protein）、白蛋白（albumin）、球蛋白（globulin）、丙型-麩胺酸轉移酶（r-glutamyl transferase; r-GT）、乳酸脫氫酶（Iactate dehydrogenase; LDH）等肝功能指數變化。實驗結果發現：這位e抗原陽性之慢性B型肝炎帶原者在T1、T2、T3及T4所測得的肝功能撿驗值皆在正常值範圍內。本個案研究顯示：這位e抗原陽性之慢性B型肝炎帶原者在經過12週中強度運動訓練後，對肝功能並無不良影響，但不宜推論至其他人。

關鍵字

e抗原陽性之慢性B型肝炎帶原者 ； 運動訓練 ； 肝功能

並列摘要

The purpose of this study was to investigate effects on liver function of e-antigen positive chronic hepatitis B carrier after 12 weeks of moderate intensity exercise. One male subject was involved in this study; with e-antigen positive chronic hepatitis B. The exercise intensity was maintained at the heart rate of 130-140 beats/minute. The frequency of the exercise was three days a week lasted for 12 weeks. Blood sample was drawn from the subject before (T1) and four weeks (T2), eight weeks (T3) and twelve weeks (T4 ) after the training. The results showed that all liver function indicators including direct bilirubin, total bilirubin, aspartate transaminase (AST), alanine transaminase (ALT), alkaline-phosphatase (Alk-p), totaI protein, albumin, gIobulin, r -glutamyl transferase (r-GT), lactate dehydrogenase (LDH) were within normal range at T1 , T2, T3, and T4. The conclusion of the study was that 12 weeks of moderate intensity exercise has no harm on liver function in this e-antigen positive chronic hepatitis B carrier, but can 110t be inferred to others.

並列關鍵字

e-antigen positive chronic hepatitis B carrier ； exercise ； liver function