The advantages of hydroponic vegetable cultivation system include (1) produce annually (2) space saving (3) high yield (4) suitable for mechanization (5) efficient use of water and fertilizers (6)low down the risk of many pests and diseases. In this study, we introduce pests and diseases mainly occur in hydroponic vegetable cultivation farms in Changhua, such as Erwinia soft rot, Pythium root rot, Phytophthora blight, aphids ,etc. Besides, we summarize the precautions for using chemical protection ,and introduce nonsynthetic reources and seed disinfection technology for reference.