「來舒衣物消毒劑－清新亞麻味（Lysol Laundry Sanitizer-Crisp Linen Scent）」能有效地殺死白色念珠菌與去除塵蟎過敏原

＂Lysol Laundry Sanitizer - Crisp Linen Scent＂ can Effectively Kill Candida albicans and Remove Dust Mite Allergens

歐柏廷(Po-Ting Ou) ； 羅凱馨(Kai-Hsn Lo) ； 蔡文城(Wen-cherng Tsai)

《檢驗及品保雜誌》 11卷4期 (2022/10) Pp. 132-137

https://doi.org/10.6573/JTQA.202210_11(4).02

摘要

吸入性過敏有許多種類的過敏原（allergens），包括塵蟎（dust mite）以及各種微生物，特別是真菌。在本研究中，吾等評估由曼倫商貿台灣有限公司（Mano Business Development Taiwan Ltd.）提供的“來舒衣物消毒劑－清新亞麻味”（Lysol Laundry Sanitizer - Crisp Linen Scent）（以下簡稱試驗物質）對白色念珠菌（Candida albicans）的殺真菌活性（fungicidal activity）。本試驗係根據美國材料試驗學會（American Society for Testing and Materials, ASTM）E2315的〈時間－殺菌方法評估抗菌活性的標準指引〉（Standard guide for assessment of antimicrobial activity using a time-kill procedure）進行。在試驗時，將0.1 mL的白色念珠菌懸浮液加入10 mL的試驗物質中（白色念珠菌的最終濃度約為10^6 CFU/mL），作用1小時，然後測定存活的白色念珠菌數量（CFU）。與未經處理的對照組相比，吾等發現試驗物質能殺死99.99%的白色念珠菌。另外，吾等還測試了試驗物質對塵蟎的去除能力，試驗時，在預先浸泡過試驗物質（試驗組）或生理食鹽水（對照組）且烘乾的羊毛織物上分別加入1,000隻蟎蟲。此試驗重複15次，並在第7天和第14天時，利用酶聯免疫吸附試驗（enzyme-linked immunosorbent assay, ELISA）對殘留在經處理和未經處理的織物上的塵蟎過敏原進行量化測定。結果顯示，處理7天後，織物上的塵蟎過敏原濃度降低88.95%，而處理14天後則降低87.32%。總之，試驗物質可有效地殺死白色念珠菌與去除塵蟎過敏原。

關鍵字

來舒衣物消毒劑 ； 白色念珠菌 ； 塵蟎過敏原

並列摘要

Inhalation allergy has many types of allergens exist, including dust mites and microorganisms, especially fungi. In this study, we evaluated the fungicidal activity of ＂Lysol Laundry Sanitizer - Crisp Linen Scent＂ (hereafter referred to as the test substance) provided by Mano Business Development Taiwan Ltd. against Candida albicans. The evaluation was conducted in accordance with ＂the standard guide for assessment of antimicrobial activity using a time-kill procedure＂ of the American Society for Testing and Materials (ASTM) E2315. In the test, 0.1 mL C. albicans suspension was added to 10 mL of the test substance (final C. albicans concentration was approximately 10^6 CFU/mL) and incubated for 1 hour, followed by determining the number (CFU) of survived C. albicans. Compared with untreated control, we found that the test substance killed 99.99% of C. albicans cells. We also tested mite removal activity of the test substance by adding 1,000 mites on a wool fabric previous soaked with test substance (test group) or saline (control group). This test was repeated 15 times, and the dust mite allergens remained on treated and untreated fabrics were quantified by enzyme-linked immunosorbent assay (ELISA) at 7 and 14 days. Results showed that dust mite allergen concentration on the fabric was reduced by 88.95% after 7 days and by 87.32% after 14 days of treatment. In conclusion, the test substance can effectively kill C. albicans and remove dust mite allergens.

並列關鍵字

Lysol Laundry Sanitizer-Crisp Linen Scent ； Candida albicans ； dust mite allergens