金屬有機骨架材料之酵素固定化

Enzyme Immobilization on Metal-Organic Frameworks

陳宜萱(Yi-Hsuan Chen) ； 蔡振彥(Chen-Yen Tsai) ； 劉婉舲(Wan-Ling Liu)

《化學》 76卷4期 (2018/12) Pp. 321-328

https://doi.org/10.6623/chem.201812_76(4).009

摘要

金屬有機骨架材料由於具有熱穩定性、孔洞可調性、易官能基修飾及高比表面積等優點，因此引起廣大的注意，漸漸開啟各種金屬有機骨架材料的應用。其中值得一提的為金屬有機骨架材料應用於酵素固定化基材方面，酵素為一種天然產物，可作為綠色催化劑，具備高度選擇性反應，但其成本與傳統催化劑相比來得更加昂貴，為了改善此缺點，近幾年來開發新穎金屬有機骨架材料做為基材的酵素固定化技術，此一技術不僅僅可提昇酵素穩定性、活性以及選擇性，並使酵素可回收再利用，改善上述溶液態酵素之缺點，大大降低反應所需的成本，故本文章將以金屬有機骨架材料的酵素固定化方法之幾大技術進行討論與介紹

關鍵字

金屬有機骨架 ； 酵素固定化 ； 綠色催化劑

並列摘要

Metal-organic frameworks (MOFs) have attracted more attention due to their unique properties such as high chemical and thermal stability, tunable pore size, ease of modification and high surface area. These features allow them to be promising candidates various applications. More recently, MOFs have been applied as support for enzyme immobilization. Enzyme is a natural product that was considered as green catalysts but its cost is higher than the conventional organic catalyst. Immobilization of enzymes on various MOFs is a novel technique that provides enzyme stability, activity and even selectivity. Herein, these main techniques for enzyme immobilization on MOFs are discussed.

並列關鍵字

Metal-organic framework ； Enzyme immobilization ； Green catalyst