口腔餵食GMP對雄性大白鼠攝食及攝水之影響

Effect of Guanosine 5'-Monophosphate, GMP On Food and Water Intake in Male Rats

楊齊生(Jimmy Chi-Sheng Yang) ； 李竹菀(Jhu-Wuan Lee) ； 周佩玉(Pey-Yu Chou) ； 王慧如(Hui-Ju Wang)

《弘光學報》 39期 (2002/05) Pp. 125-128

https://doi.org/10.6615/HAR.200205.39.14

摘要

海鮮食物中的游離胺基酸及核苷酸可增強食物之鮮美度，所引起令人歡喜口感之味覺被稱為Umami。在食品工業中使用的高鮮味精成分之一即是核苷酸中之一種－Guanisine 5’-Monophosphate (GMP)，本次實驗是以口腔餵食成熟雄性Sprague-Dawley大白鼠GMP每日兩次連續五天餵食，觀察其攝食及攝水量之變化。由結果得知GMP (0.2mg或0.2mg/day/rat)顯著增加大白鼠全天攝食量，但對攝水量則無顯著性之影響，因此本實驗推論GMP有促進雄性大白鼠食慾之作用。

關鍵字

GMP ； 攝食

並列摘要

Free amino acid and derivatives of 5'-ribonucleotide are widely used as food additive to enhance palatability of food to produce the spcial taste, called Umami. Guanosine 5'-monophosphate (5'-GMP) is also used as ingridient of super-seasoning to improve the taste of food in the food industry in Taiwan. In this study we show that intraorally feeding adult male Sprague-Dawley rats 5'-GMP (0.2mg or 2mg/day/rat) twice daily for 5 days significantly increased average food intake, but not water intake. These results suggest that 5'-GMP increases feeding via mechanism of taste in the tongue.

並列關鍵字

guanosine 5'-monophosphate ； umami ； food intake

參考文獻

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