In this study, the chemical compositions of the Plectranthus amboinicus (PA) essential oils from water distillation extraction in three different months were analyzed by gas chromatography-mass spectroscopy. The results were shown that the contents of volatile components of PA in March are significantly more than in May and in June. It is also found that the m-cymene exists only in March. The contents of the juniper camphor and the alloaromadendrene of PA in May are more than in March and in June, but the 2-carene and the 3-carene are less than in March and in June. In different seasons the harvesting and extraction of PA essential oils, their compositions and the contents will be significant differences.