- 期刊
- OpenAccess
Plasma Brain Natriuretic Peptide (BNP) as an Indicator of Left Ventricular Function, Early Outcome and Mechanical Complications after Acute Myocardial Infarction
並列摘要
Aims: This study investigated the prognostic value of B type natriuretic peptide (BNP) in acute myocardial infarction (AMI) patients and its relation with left ventricular function and post-myocardial infarction complications. Methods: In this cross-sectional study, plasma BNP level was measured for 42 consecutive patients (mean ± SD: 61.6 ± 10.85 years old) with acute ST elevation myocardial infarction (MI) and 42 healthy, age and gender matched subjects. Result: BNP level in AMI patients were significantly higher than control group (P ＜ 0.001). Regarding to infarct location, the highest BNP level measured in inferoposterior MI (BNP = 4436.63 ± 6188.159 pg/ml) and the lowest one indicated in standalone inferior MI (BNP = 598.83 ± 309.867 pg/ml (P = 0.071). There was significant reverse relation between BNP and EF (P = 0.006, OR = -0.47) and a significant relationship between BNP and killip classification (P = 0.036). There was no significant relation between diastolic and rightventricular function and BNP level (P = 0.61, P = 0.21). The highest BNP level was detected in LV septal rupture and false aneurysm (P = 0.02) and in ventricular tachycardia, but without significant relationship (P = 0.25). Conclusion: After the onset of AMI, BNP blood level can be used as an important predictor for left ventricular dysfunction, killip classification, early mechanical complications and cardiac death.
延伸閱讀
- Adhyapak, S. M., Menon, P. G., Varghese, K., Mehra, A., Lohitashwa, S., & Fantini, F. (2017). Improvements in Regional Left Ventricular Function Following Late Percutaneous Coronary Intervention for Anterior Myocardial Infarction. Clinical Medicine Insights: Cardiology, 2017(), 1-7-017. https://doi.org/10.1177/1179546817746636
- Liu, C. W., Chen, J. H., Tseng, G. S., Chen, K. H., Hwang, J. J., Yang, W. S., & Wu, Y. W. (2020). Association between Low-Grade Inflammation and Left Ventricular Diastolic Dysfunction in Patients with Metabolic Syndrome and Hyperuricemia. Acta Cardiologica Sinica, 36(5), 483-492. https://doi.org/10.6515/ACS.202009_36(5).20200406A
- Swiatkiewicz, I., Kozinski, M., Magielski, P., Fabiszak, T., Sukiennik, A., Navarese, E. P., Sypniewska, G. O., & Kubica, J. (2012). Value of C-Reactive Protein in Predicting Left Ventricular Remodelling in Patients with a First ST-Segment Elevation Myocardial Infarction. Mediators of Inflammation, 2012(), 376-386. https://doi.org/10.1155/2012/250867
- Chuang, C. P., Lo, H. M., Wu, C. Y., Jong, Y. S., & Ho, F. M. (2007). N-terminal Pro-brain Natriuretic Peptide as a Prognostic Predictor in Critical Care Patients with Acute Cardiogenic Pulmonary Edema. Acta Cardiologica Sinica, 23(1), 20-28. https://www.airitilibrary.com/Article/Detail?DocID=10116842-200703-23-1-20-28-a
- Wang, W. H., Hsiao, S. H., Chiou, K. R., Liu, C. P., Huang, W. C., Lin, S. K., Kuo, F. Y., Cheng, C. C., & Lin, K. L. (2012). Limited Efficacy of Myocardial Tissue Doppler for Predicting Left Ventricular Filling Pressure, Severe Pulmonary Edema, and Respiratory Failure in Acute Myocardial Infarction. Acta Cardiologica Sinica, 28(3), 206-215. https://www.airitilibrary.com/Article/Detail?DocID=10116842-201209-201209140012-201209140012-206-215