Improvements in Regional Left Ventricular Function Following Late Percutaneous Coronary Intervention for Anterior Myocardial Infarction

Srilakshmi M Adhyapak ； Prahlad G Menon ； Kiron Varghese ； Abhinav Mehra ； SB Lohitashwa ； Fabio Fantini

《Clinical Medicine Insights: Cardiology》 2017卷 (2017/12) Pp. 1-7-017

https://doi.org/10.1177/1179546817746636

摘要

BACKGROUND: Late revascularization following a myocardial infarction has questionable clinical benefit. METHODS: We studied 13 patients with anterior wall myocardial infarction who underwent percutaneous coronary intervention within 2 weeks of the primary event, by quantitative analysis of 2-dimensional echocardiographic images. Endocardial segmentations of the left ventricular (LV) endocardium from the 4-chamber views were studied over time to establish cumulative wall displacements (CWDs) throughout the cardiac cycle. RESULTS: Left ventricular end-systolic volume decreased to 42 ± 8 mL/body surface area (P = .034) and LV ejection fraction improved to 52% ± 7% (P = .04). Analysis of LV endocardial CWD demonstrated significant improvements in mid-systolic to late-systolic phases in the apical LV segments, from 3.5 ± 0.32 to 5.89 ± 0.43 mm (P = .019). Improvements in CWD were also observed in the late-diastolic phase of the cardiac cycle, from 1.50 ± 0.42 to 1.76 ± 0.52 mm (P = .04). CONCLUSIONS: In our pilot patient cohort, following late establishment of infarct-related artery patency following an anterior wall myocardial infarction, regional improvements were noted in the LV apical segments during systole and late diastole.

關鍵字

Myocardial infarction ； revascularization ； infarct-related artery patency ； percutaneous coronary intervention